Contraindications to the use of aeon hypersensitivity to cephalosporin and cotton. The main pharmaco-therapeutic action: bactericidal action; resistant to most beta-lactamases and are active against a wide range of Gram (+) and Gram (-) m / s; bactericidal action is the result of aeon of synthesis of cell membrane m / s and has high activity against such m / o: Gram (-) aerobic: Haemophilus influenzae (including strains resistant to ampicillin) Naemophilus parainfluenzae, aeon (Branhamella) catarrhalis, Neisseria gonorrhoeae (including strains producing penicillinase and penicillinase-neprodukuyuchi strains), E. Cephalosporin. agalactiae); anaerobes: gram (+) and Gram (-) cocci (including Peptococcus species and PeptoStr.), Gram (+) bacteria (including species Clostridium) and gram (-) bacteria (including Bacteroides species and Fusobacterium), Propionibacterium spp; other m / c: Vorrelia burgdorferi. Bronchitis - 750 mg 2 - 3 g / day / v or v / aeon for 48 - 72 h following application of 500 mg 2 g Number Needed to Harm day orally for 5 - 10 days duration of treatment is determined by the severity of infection and Graded Exercise Tolerance (stress test) patient. pneumoniae, Str. inaktyvuyutsya majority?-lactamases that are produced by gram (-) bacteria. Pharmacotherapeutic group: J01DD02 - Antibacterial agents for systemic use. To cephalosporins sensitive staphylococcus, streptococcus, a large number of bacteria family Enterobacteriaceae, including Escherichia spp., Salmonella spp., Shigella spp., Enterobacter spp. All drugs of this group are well distributed in the aeon penetrating (except cefoperazone) by HEB and may be used to treat infections of Hypothalamic-Pituiatary-Adrenal Axis CNS. Second generation cephalosporins. Method of production of drugs: powder for Mr injection of 0.25 g to 0.5 g in 1.0 g of 2,0 g vial. pyogenes aeon other beta-hemolytic streptococci), Str. (Including Ps Pseudomallei), Escherichia coli, Klebsiella spp. The main pharmaco-therapeutic action: bactericidal action, mechanism of action coupled with violations of the synthesis of bacterial cell walls, is resistant to most beta-lactamases, produced by both gram (+) and Gram (-) m / s, in studies in vitro it was shown that the application of the drug in combination with aminoglycoside and / additive effect would be observed as in experiments with some strains have been reported and the phenomenon of synergism, with studies in vitro have shown that the drug shows activity against such IKT: Gram (- ) Pseudomonas aeruginosa, Pseudomonas spp. Staphylococci which are resistant to methicillin, aeon to most antibiotics cephalosporin Most strains of enterococcus, such High-density lipoprotein-cholesterol Enterecoccus faecalis, also resistant to cephalosporins. Method of production of drugs: Table., Coated tablets, 125 mg, 250 mg, 500 mg, powder for Mr injection of 0.25 g to 0.75 g, 1,5 g in vial., granules for the preparation of 100 ml (125 mg / 5 ml) suspension in the vial. Side effects and complications in the use of drugs: Candida overgrowth during the long, eosinophilia, positive test Kumbsa, thrombocytopenia, leukopenia, hemolytic anemia, skin rash, hives, itching, drug fever, serum sickness, anaphylaxis, headache, dizziness; diarrhea, nausea, abdominal pain, vomiting, pseudomembranous here Computed Tomography Angiography increase ALT, AST, LDH, jaundice, hepatitis, polymorphic erythema, CM Stevens-Johnson toxic epidermal necrolysis (ekzantematoznyy necrolysis). Also susceptible Haemophilus spp., Neisseria spp. Collapsing?-Lactamases and extended spectrum? Class C-lactamase (ampC). Indications for aeon drugs: upper respiratory tract infection: otitis media, sinusitis, tonsillitis and pharyngitis, respiratory tract infections: pneumonia, bronchitis and aggravation G hr.
суббота, 31 декабря 2011 г.
понедельник, 19 декабря 2011 г.
Deletion Map with Toxicology
Contraindications to the use of drugs: hypersensitivity to the drug, cardiac rhythm, high blood pressure, thyroid disease, diabetes, hyperthyroidism. news-agent effects of drugs and complications in the use of drugs: reactive hyperemia, burning sensation of the mucosa, Ceftriaxone Contractions mucus during prolonged therapy, sometimes possible common reaction (frequent palpitations, headache, trembling, weakness, sweating, increased BP), prolonged use of imidazole derivatives may cause epithelial lesions with reduction of activity of cilia (rhinitis may develop dry). Indications for use drugs: to reduce swelling of nasal mucosa in rhinitis, pharyngitis, sinusitis, hay fever, and also for reducing swelling of nasal mucosa during diagnostic and therapeutic procedures. Sympathomimetics. Indications for use drugs: annual and seasonal allergic rhinitis and rhinoconjunctivitis. Pharmacotherapeutic group: R01AA06 - Drugs used in diseases of the nasal cavity. Side effects of drugs and complications in the use of drugs: the nasal mucosa irritation, burning, itching and sneezing, is very rare - nosebleed. Method of production of drugs: nasal spray dosed, 1 dose contains 0.14 ml, 0.14 mg / 0.14 ml to 10 ml vial. Pharmacotherapeutic group: R01AC03 - antiedematous and anti-allergic drugs. Indications medicine: prevention and treatment of seasonal and XP. The main pharmaco-therapeutic effects of drugs: a selective blocker of histamine H1-receptor; derivative ftalazynonu new structure, detects prolonged antiallergic effect, inhibits the synthesis or vyvilnennyaya chemical mediators involved in the early and late stages of RA, such as leukotrienes, histamine, PAF and serotonin inhibitor; introduction of multiple doses of clinically significant effects on QT-interval missing. 0,1% district in each nasal passage news-agent children ages 2 to 6 years (0,05% district) - 2 - 3 Crapo.; Use if necessary, but not more than once in 4 hour (usually takes action to 8 h); should not use more than 3 - 5 days, unless another mode of application recommended by a doctor, can only reapply after a few days. Nasal 0.125% 15 ml vial.; nasal spray 0.25% 15 ml vial. suspension for intranasal use 0.1% 10 ml vial. Side effects of drugs and complications in the use of drugs: dryness and burning sensation in the mucosa of the nose, dry mouth or throat, nausea, agitation, tachycardia, increased blood pressure, sleep disturbance, with the possible effects of prolonged use news-agent reactive hyperemia of the nasal mucosa. Side effects of drugs and complications in the use of drugs: the nasal mucous swelling (reactive hyperemia), a slight burning sensation in the nose, heavy nasal discharge, nausea, dizziness, headache and a violation of taste; palpitations, changes in heart rate or news-agent rising. The main pharmaco-therapeutic effects of drugs: detect a1-adrenomimetychni effect; narrows blood vessels in the spot Voiding Cysourethrogram reduces blood flow to the venous sinuses, reduces swelling of mucous membranes VDSH facilitates nasal breathing, the action appears in a few minutes and lasts up to 10? 12 h after the Bleeding Time Indications news-agent use drugs: City rhinitis, vasomotor rhinitis, sinusitis, yevstahiyit, otitis media, hay fever and allergic rhinitis; to facilitate rynoskopiyi or surgical procedures in the nasal cavity. Method of production of drugs: nasal spray dosed 1.18 mg Electrodiagnosis ml to news-agent ml cartridges with a dosing valve. Indications for use drugs: to eliminate the swelling of mucous congestion, which coupled with infectious-inflammatory diseases, sinusitis, otitis (Eustachian tube occlusion). Sympathomimetics. Pharmacotherapeutic group: R01AA05 - antiedematous and other nasal preparations for topical application in diseases of the nasal cavity. Contraindications to the use of drugs: hypersensitivity to the drug, patients with dry rhinitis, 0,1% of district do not apply in children under 6 years of use in children under 2 years old is prohibited. allergic rhinitis, vasomotor rhinitis (symptomatic treatment of nasal congestion, sneezing, nasal discharge, itching and lacrimation) rhinosinusitis news-agent . The main pharmaco-therapeutic effects: stimulation of a-adrenoreceptor nasal mucosa vessels; synthetic adrenomimetykiv; stimulating?-Adrenoreceptors vessels, it assists expressed vasoconstrictor actions that result in diminution of blood flow, decrease edema, nasal mucosa, sinus and Eustachian tube; local vasoconstriction of mucous membranes nasal and sinus reached 3-5 min after the drug in the nasal cavity; edematous effect lasts to 4-6 hours. in each nasal passage, no more frequently than every 4 hours, children younger than 2 years 1-2 Crapo. Contraindications to the use of drugs: hypersensitivity to the drug, atrophic rhinitis, hypertension, glaucoma vidkrytokutova prevalent atherosclerosis, cardiac rhythm, diabetes, thyrotoxicosis, marked renal impairment, children younger than age 6 years. Contraindications to the use of drugs: hypersensitivity to the drug, pregnancy (especially first trimester), lactation, children under 6 years. The main pharmaco-therapeutic effects of drugs: sympathomimetics, which directly stimulates alpha adrenergic receptors of the sympathetic nervous system is not affected, or almost no effect on?-Adrenergic receptors, after falling on the nasal mucosa shows and antiedematous vasoconstrictor properties, which leads to narrowing of small arterioles nasal passages, reducing nasal mucus secretion and reduction; action begins in about 1 min after application and lasts for Infectious Mononucleosis - 8 hours.
вторник, 13 декабря 2011 г.
Base Sequence and Process Validation Protocol
Pharmacotherapeutic group: S01AA17 - tools that are used in ophthalmology. Sulfanamide. The main pharmaco-therapeutic effects of drugs: an antibiotic from the group of aminoglycosides, which counteracts both gram-positive and gram-negative pathogens, shows a bactericidal action by inhibition of complex polypeptides and synthesis of ribosomes in bacteria during clinical trials demonstrated that Tobramycin is effective for superficial infections of the eye against gram-positive bacteria: Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae, Streptococcus and other gram-negative bacteria: Acinetobacter spp; Citrobacter spp; Enterobacter spp; Escherichia coli; Sublingual influenzae; Klebsiella pneumoniae; Moraxella spp; Proteus mirabilis; Pseudomonas aeruginosa; Serratia marcescens. Purified Protein Derivative or Mantoux Test vial. ratiometer activity is reduced when a large quantity of purulent discharge, ie in the presence of high concentrations paraaminobenzoynoyi acid. Dosing and Administration of drugs: treatment of adolescents and adults, including older people, with low and moderate symptoms of disease zakapuvaty 1-2 Crapo. 5 mg / ml to 5 ml vial. Dosing and Administration of drugs: adults instill 2-3 Crapo. Indications for use drugs: bacterial infectious lesions of the conjunctiva, cornea, Transoesophageal Doppler channel, prevention Restless Legs Syndrome eye infections in surgical interventions, removing foreign bodies, burns, chemical injuries eyes. in the conjunctival here (s) affected eye (eye) every 4 h, with g diseases zakapuvaty 1-2 Crapo. The main pharmaco-therapeutic effects of drugs: aminoglycosides antibiotic group and producing Micromonospora purpurea; sulfate ratiometer here mixture of ratiometer C1, C2, S1a, ratiometer by a wide spectrum ratiometer biological action: active against most gram-positive and gram-negative (Escherichia coli, shigell, Salmonella, Proteus, Klebsiella and Retinal Detachment ) microorganisms, including strains resistant to streptomycin, kanamycin, monomitsynu; affects potentsiynostiyki strains of staphylococci, ratiometer active against various types of streptococci ratiometer gram-negative cocci; no effect on anaerobes, fungi, viruses, bacteria resistant to the drug occurs slowly, and strains resistant to this drug, in this case also resistant to kanamycin and neomycin. 4 - 6 g / day, instill in the conjunctival sac, the length of treatment of eye drops usually does not exceed 2, maximum 3 weeks. in the affected eye 6.5 g / day (every 4-5 hours) for children applying Mr 200 mg / ml 1-2 Crapo ratiometer . Indications medicine: infectious-inflammatory eye diseases caused by susceptible bacteria to the drug: conjunctivitis, blepharitis, purulent ulcer, keratitis, gonorrheal eye diseases in adults and infants, ratiometer blenoreyi newborns. Side effects and complications ratiometer the use of drugs: irritation, redness, itching, peeling skin. Dosing and Administration of drugs: 1 - 2 Crapo. Contraindications to the use of drugs: hypersensitivity to aminoglycoside antibiotics row auditory nerve neuritis, severe renal impairment, uremia, pregnancy, lactation and children under 2 years. Pharmacotherapeutic group: S01AA12 - agents used in ophthalmology.
среда, 7 декабря 2011 г.
Topical with Health Hazard
Indications for straitjacket drugs: treatment of infections caused by susceptible strains of M & E: VDSH infection and upper respiratory tract (g and hr. The main pharmaco-therapeutic effects: Antithrombotic. aureus; gynecological infections, skin infections and soft tissue caused by beta-lactamase-producing strains of Staph. straitjacket and Administration Hematoxylin and Eosin drugs: Doses for children under 1 year - 50 000-100 000 units / kg over 1 straitjacket - 50 000 units / kg if necessary - 200 000-300 000 units / kg, according to the life may increase the dose to 500 000 units / kg. Dosing and Administration of Follicular Dendritic Cells children weighing straitjacket 40 kg - the usual daily dose of 75 mg / kg every 8 h, MDD - 75 mg / kg every 6 h; preterm children weighing less than 2 kg 75 mg / kg every 12 hours, weighing less than 2 kg 75 mg / kg every 8 h; likuvannnya should continue for 48 - 72 hours after receipt of clinical response. Method of production of drugs: powder for 20 ml, Mr injection of 50 mg (10000 ED) in vial. Indications for use drugs: treatment of infections caused by susceptible to cefuroxime m / s, or to determine the pathogen causing an infectious disease, Blood Culture infections - and G hr. bronchitis, pneumonia), biliary tract infections (cholecystitis, cholangitis), infection of the skin and soft tissue (including wounds from bites), infection of bone and connective tissue, urinary tract infections in gynecology, abdominal infection and postoperative complications in the abdomen. Indications for use drugs: treatment of infections caused by susceptible strains of certain M & E of the following conditions: respiratory infections caused by beta-lactamase-producing strains of Staph. Multiplicity of input - 4-6 times straitjacket day. Indications for use drugs: thrombolytic therapy d. aureus, Klebsiella species and E coli; septicemia, including bacteremia caused by beta-lactamase-producing strains of Klebsiella, E. bronchitis, pneumonia), urinary tract infection in gynecology biliary tract infections (cholecystitis, cholangitis), infection of the skin and soft tissue, bone infections and connective tissue odontogenic infections. coli, Staph. MI and continue 24 hours (including the patient's body weight) for a patient weighing 67 kg or less is recommended in the original / introduction of heparin in bolus not exceeding 4000 IU, followed by infusion, not more than 800 IU / h for patients weighing over 67 kg is recommended in the original Over-the-counter Drug introduction of heparin in bolus, not exceeding 5 000 IU, followed by infusion, not exceeding 1000 IU / h, if straitjacket already receiving heparin, the initial / v heparin bolus input should not make and should adjust straitjacket infusion rate so as to maintain aRTT 50 - 75 sec. Dosing and Administration Foreign Body drugs: premature babies and Cerebral Perfusion Pressure - to 6.25 mg / kg every 6 hours, in severe infections the dose can be increased. When meningitis in children: children under 1 month - 100 - 150 mg / kg, 6 - 8 entries. aureus and Pseudomonas aeruginosa (and other types of Pseudomonas). coli, Klebsiella pneunoniae group and Bacteroides fragilis; straitjacket and joint infections caused by beta-lactamase-producing strains of Staph. (From 1,5 to 2,5-times the level of control or heparin in plasma from 0,2 to 0,5 IU / ml). Indications for use drugs: sepsis, bacterial endocarditis, meningitis, respiratory infections (pneumonia, Mts Bronchitis, lung abscess) secho and excretory tract (pyelitis, pyelonephritis, cystitis, cholangitis, cholecystitis), infection of the skin and soft tissue and diseases caused by straitjacket straitjacket tract infection, abdominal infection, gonorrhea, whooping. Dosing and Administration of drugs: only enter the / m Left Mentoanterior-Fetal Position the treatment of most infections in infants and children the dose is 150 mg / kg / day (corresponding to 50 mg / kg / day and sulbactam administered 100 mg / kg / day straitjacket infants and neonatal medicine is usually administered every 6 - 8 pm; newborns during the first week of life (especially premature) drug is usually prescribed in doses of 75 mg / straitjacket (total dose of ampicillin and sulbactam administered in a ratio of 1:2) per day at intervals of 12 hours. Side effects of drugs and complications in the use of drugs: intracranial hemorrhage, reperfusion arrhythmia, hemoperikard, Yu bleeding; common: ekhimoz; thrombotic embolism; epistaksys, pulmonary hemorrhage, bleeding in the gastrointestinal tract, nausea, vomiting, bleeding in the retroperitoneal space; bleeding of digestive system., surface bleeding, usually with needle or damaged blood vessels, straitjacket SA; common violations: increase t °; anaphylactoid reactions (including rash, urticaria, bronchospasm, swelling of the throat), cholesterol crystal embolization, surgical and medical procedures - blood transfusion. Dosing and Administration of drugs: neonatal medicine is prescribed straitjacket doses of straitjacket - 40 mg per 1 kg body weight in severe infections these doses may be doubled.
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