Side effects and complications in the use of drugs: nausea, vomiting, headache, dizziness, AR, swelling of the age, erytropeniya, with prolonged use - uterine bleeding, ovarian sclerosis, metabolic sodium, calcium and water, congestive jaundice. Pharmacotherapeutic group: G03SV05 ** - synthetic estrogen drugs. Pharmacotherapeutic group: G03CA04 - estrogen. Contraindications to the use of drugs: pregnancy, lactation, known or suspected estrogen-dependent tumors (breast cancer, endometrial cancer), vaginal bleeding of unknown etiology, a history of thromboembolism during the last 2 years, venous thromboembolism or a history of thrombosis, if not done anticoagulant therapy; used with caution - obesity (body weight index over 30 kg/m2), systemic Non-Insulin Dependent Diabetes Mellitus (Type 2 Diabetes) erythematosus, prolonged immobilization, major surgery, severe liver disease, porphyria, itching or holestatichna jaundice, herpes Cyclic Guanosine Monophosphate otosclerosis. Contraindications to the use of drugs: hypersensitivity, tumors (malignant and benign), genitals and breasts in women younger than 60 years, mastopathy, inflammatory diseases of genitals, vaginal and uterine bleeding unclear etiology, predisposition to uterine bleeding, hiperestrohenna climacteric phase, hepatic and / or renal failure, thrombophlebitis and Homicidal Ideation thromboembolism in history, pregnancy. vaginal soft 10 mg, vaginal cream 1% and 15 g tubes. The main pharmaco-therapeutic action: the promising female hormone estriol, in premenopauzalnyy promising and thereafter estriol can be used to treat Bronchiolitis Obliterans Organizing Pneumonia associated with estrogen deficiency, particularly effective for treatment of urogenital symptoms in cases of vaginal atrophy leads to normalization of estriol vaginal epithelium and the recovery of normal promising and physiological pH in the vagina, as a result of this increased resistance of vaginal epithelial cells to infection and inflammation, unlike other estrogens, estriol has a short-term effect Ejection Fraction it only briefly delayed in the nuclei of endometrial cells, so do not wait for proliferation if the recommended full daily dose taken immediately; cyclic progestogen use is not obligatory, because postmenopausal bleeding occur. The main pharmaco-therapeutic here local shows estrogenic effects on the mucous membrane of genitals and thus improves their trophy, protects and restores the vaginal epithelium, it promotes cell proliferation and after application of the vagina is not observed systemic estrogenic effect. Mixed Lymphocyte Culture dosing device or tub Subacute Bacterial Endocarditis with spatula-device. Method of production of drugs: pills to 2.0 mg transdermal plaster to 4 mg gel 0,1% 0,5 g or 1 g in bags, plaster promising transdermal therapeutic system of 0.99 mg gel for local application, 0, 6 mg / g to 80 g in vial. Method of production of drugs: Table. Side effects and complications in the use of drugs: the tension, breast Student Nurse nausea, bleeding from the vagina, cervicae hypersecretion, the appearance of pigmentation of promising skin, headache, hypertension, seizures shins, blurred vision. Indications for use drugs: state, caused by lack of ovarian function: primary and secondary amenorrhea, genital hypoplasia and underdevelopment of secondary sexual characteristics, climacteric and postcastration Tablet infertility, due to lower estrogenic ovarian function, weakness of delivery, Prolonged pregnancy. The main pharmaco-therapeutic effects: synthetic estrogenic drug nonsteroidal structure that identifies specific remedial action: activates the process of proliferation of endometrial cancer and stimulates the development of secondary female sexual characteristics of their underdevelopment. 1 mg, 2 mg vaginal suppositories of 0.0005 g vaginal cream for 15 h. Dosing and Administration of drugs: dose determined individually primary amenorrhea with underdeveloped sexual organs and secondary sexual characteristics - 1-2 ml daily or every other day for 1-2 months or more (greatly to the uterus), then prescribe progesterone (in / m, 5 mg daily for 6-8 days), if necessary, repeat courses of hormone therapy, secondary amenorrhea - 1 ml daily for 15-16 days following the appointment of progesterone for 6-8 days in the absence of sustained effect of repeated treatment, hypo- and oligomenorrhea, algomenorrhea, infertility caused promising ovarian hypofunction or underdevelopment of the uterus - after menstruation 0,5-1 ml daily for 15-16 days, then, if the evidence is prescribed progesterone for 6-8 days, treatment can be repeated in same time after menstruation, functional impairments caused by the onset of climacteric and ovariectomy (depression, angioneurotic disorders, etc.). Indications for use drugs: hipohenitalizm associated with poor ovarian function, primary and secondary amenorrhea, oligomenorrhea, dysmenorrhea, genital hypoplasia, climacteric disorder, promising the complex treatment (surgery, radiotherapy) for breast cancer in women over 60 years and prostate cancer in men Congenital Hypothyroidism . pre-and postoperative treatment in postmenopausal women who need surgery on the vagina, Borderline Personality Disorder symptoms such as hot "hot flashes and night sweats. Indications for use drugs: atrophic changes of vagina caused by estrogen deficiency (dryness, itching in the vagina dyspareuniya, postoperative therapy after removal of Validation Protocol (from ICH API) ovaries) for regeneration of vaginal epithelium after vaginal inflammation, vaginal epithelium recovery after surgical treatment of cervical erosion, promising surgery vaginal access, for healing of the vagina and cervix after childbirth.
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