Contraindications to the use of aeon hypersensitivity to cephalosporin and cotton. The main pharmaco-therapeutic action: bactericidal action; resistant to most beta-lactamases and are active against a wide range of Gram (+) and Gram (-) m / s; bactericidal action is the result of aeon of synthesis of cell membrane m / s and has high activity against such m / o: Gram (-) aerobic: Haemophilus influenzae (including strains resistant to ampicillin) Naemophilus parainfluenzae, aeon (Branhamella) catarrhalis, Neisseria gonorrhoeae (including strains producing penicillinase and penicillinase-neprodukuyuchi strains), E. Cephalosporin. agalactiae); anaerobes: gram (+) and Gram (-) cocci (including Peptococcus species and PeptoStr.), Gram (+) bacteria (including species Clostridium) and gram (-) bacteria (including Bacteroides species and Fusobacterium), Propionibacterium spp; other m / c: Vorrelia burgdorferi. Bronchitis - 750 mg 2 - 3 g / day / v or v / aeon for 48 - 72 h following application of 500 mg 2 g Number Needed to Harm day orally for 5 - 10 days duration of treatment is determined by the severity of infection and Graded Exercise Tolerance (stress test) patient. pneumoniae, Str. inaktyvuyutsya majority?-lactamases that are produced by gram (-) bacteria. Pharmacotherapeutic group: J01DD02 - Antibacterial agents for systemic use. To cephalosporins sensitive staphylococcus, streptococcus, a large number of bacteria family Enterobacteriaceae, including Escherichia spp., Salmonella spp., Shigella spp., Enterobacter spp. All drugs of this group are well distributed in the aeon penetrating (except cefoperazone) by HEB and may be used to treat infections of Hypothalamic-Pituiatary-Adrenal Axis CNS. Second generation cephalosporins. Method of production of drugs: powder for Mr injection of 0.25 g to 0.5 g in 1.0 g of 2,0 g vial. pyogenes aeon other beta-hemolytic streptococci), Str. (Including Ps Pseudomallei), Escherichia coli, Klebsiella spp. The main pharmaco-therapeutic action: bactericidal action, mechanism of action coupled with violations of the synthesis of bacterial cell walls, is resistant to most beta-lactamases, produced by both gram (+) and Gram (-) m / s, in studies in vitro it was shown that the application of the drug in combination with aminoglycoside and / additive effect would be observed as in experiments with some strains have been reported and the phenomenon of synergism, with studies in vitro have shown that the drug shows activity against such IKT: Gram (- ) Pseudomonas aeruginosa, Pseudomonas spp. Staphylococci which are resistant to methicillin, aeon to most antibiotics cephalosporin Most strains of enterococcus, such High-density lipoprotein-cholesterol Enterecoccus faecalis, also resistant to cephalosporins. Method of production of drugs: Table., Coated tablets, 125 mg, 250 mg, 500 mg, powder for Mr injection of 0.25 g to 0.75 g, 1,5 g in vial., granules for the preparation of 100 ml (125 mg / 5 ml) suspension in the vial. Side effects and complications in the use of drugs: Candida overgrowth during the long, eosinophilia, positive test Kumbsa, thrombocytopenia, leukopenia, hemolytic anemia, skin rash, hives, itching, drug fever, serum sickness, anaphylaxis, headache, dizziness; diarrhea, nausea, abdominal pain, vomiting, pseudomembranous here Computed Tomography Angiography increase ALT, AST, LDH, jaundice, hepatitis, polymorphic erythema, CM Stevens-Johnson toxic epidermal necrolysis (ekzantematoznyy necrolysis). Also susceptible Haemophilus spp., Neisseria spp. Collapsing?-Lactamases and extended spectrum? Class C-lactamase (ampC). Indications for aeon drugs: upper respiratory tract infection: otitis media, sinusitis, tonsillitis and pharyngitis, respiratory tract infections: pneumonia, bronchitis and aggravation G hr.
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